What is the unspoken fatal epidemic of our time? And the greatest predictor of overall health, happiness, job satisfaction, and resiliency? Loneliness. As a clinical cardiologist, I am committed to the health and well-being of my patients. isolation — wedded to a feeling of helplessness — are core elements in the epidemic of burnout affecting roughly one-half of all U.S. health care providers. Impact on health Compelling data on the crisis of social isolation and loneliness is reported: A 2017 overview of 40 systematic reviews on the public health consequences of social isolation and loneliness. Bottom line: Loneliness impacts our overall health, well-being, longevity, cardiovascular disease outcomes, early death, depression, anxiety, cancer outcomes, suicide, and dementia. Call to action What’s your solution? What will you do differently this week? At work? At home? Many resources and solutions are available online. Once we begin to seek and share our solutions to the crisis of social isolation and loneliness, we are no longer alone. Jonathan Fisher is a cardiologist.